News & Events

TIGOR aims to share updates related to events, media appearances, grants secured, and other accomplishments by the many members of the TIGOR community. If you have any questions about these news items or something to contribute, please contact

Exploiting Existing Molecular Scaffolds for Long-Term COVID Treatment

In a recently published study on ACS Medicinal Chemistry Letters, the research team highlights past and recent findings in essential coronavirus proteins, including RNA polymerase machinery, proteases, and fusion proteins, that offer opportunities for the design of novel inhibitors of SARS-CoV-2 infection. By discussing the current inventory of viral inhibitors, the research team identifies molecular scaffolds that may be improved by medicinal chemistry efforts for effective therapeutics to treat current and future coronavirus-caused diseases.

Krishna Kumar and Tania J. Lupoli

Obesity: The risk lurking in the shadows during the COVID-19 pandemic

As the United States grapples with the ever-growing number of COVID-19 cases, it is becoming more obvious that inequality — including poor access to health care for low-income individuals and high rates of poverty and economic hardship — is currently contributing to the emergency.

Adolfo G. Cuevas and Michael V. Stanton

Integrating Systems and Sectors Towards Obesity Solutions

The workshop hosted by the National Academies of Sciences, Engineering and Medicine will look at existing societal systems that have the potential to shape public health, and consider opportunities for systems change as they relate to obesity solutions. Presenters will explore how systems and contributing factors like inequity (i.e. social determinants), power dynamics, relationships, capacity, and political will affect systems that can influence obesity, and how they can impact effective communications and cross-sector collaboration to address obesity.

The National Academies of Sciences, Engineering, and Medicine

TIGOR Grants for Obesity Research 2019-2020, Round 2

Announcement of funding recipients: Jennifer DuPont, Alice H. Lichtenstein, Nirupa R. Matthan, Patrick Catalano, and Andrew Greenberg

Study: Losing weight—and keeping it off—linked to cardiometabolic benefits

People who lose weight and keep it off can stabilize or even improve their cardiometabolic risk factors compared to people who regain weight, finds a new study led by researchers from the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts.

Jean Mayer USDA Human Nutrition Research Center